Structure of PDB 2fp2 Chain B

Receptor sequence
>2fp2B (length=163) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
SQLAELVDAAAERLEVADPVAAFKWRAQLPIEDSGRVEQQLAKLGEDARS
QHIDPDYVTRVFDDQIRATEAIEYSRFSDWKLNPASAPPEPPDLSASRSA
IDSLNNRMLSQIWSHWSLLSAPSCAAQLDRAKRDIVRSRHLDSLYQRALT
TATQSYCQALPPA
3D structure
PDB2fp2 1.6A Crystal Structure of the Secreted Chorismate Mutase from Mycobacterium tuberculosis: Novel Fold Topology Revealed
ChainB
Resolution1.64 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R49 K60 D69 T105 E106 E109 R134
Catalytic site (residue number reindexed from 1) R13 K24 D33 T69 E70 E73 R98
Enzyme Commision number 5.4.99.5: chorismate mutase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TSA B R49 K60 I67 E68 D69 R72 Q76 I102 T105 E106 E109 R134 R13 K24 I31 E32 D33 R36 Q40 I66 T69 E70 E73 R98
Gene Ontology
Molecular Function
GO:0004106 chorismate mutase activity
GO:0005515 protein binding
GO:0016853 isomerase activity
Biological Process
GO:0009697 salicylic acid biosynthetic process
GO:0046417 chorismate metabolic process
Cellular Component
GO:0005576 extracellular region

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Cellular Component
External links
PDB RCSB:2fp2, PDBe:2fp2, PDBj:2fp2
PDBsum2fp2
PubMed16499927
UniProtP9WIB9|SCMU_MYCTU Secreted chorismate mutase (Gene Name=Rv1885c)

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