Structure of PDB 2fgh Chain B

Receptor sequence
>2fghB (length=721) Species: 9796 (Equus caballus) [Search protein sequence]
VEHPEFLKAGKEPGLQIWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQL
RNGILQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFE
SATFLGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLLQVKGRRVVRATEV
PVSWESFNNGDCFILDLGNNIYQWCGSKSNRFERLKATQVSKGIRDNERS
GRAQVSVFEEGAEPEAMLQVLGPKPTLPEATENRKLAKLYKVSNGAGPMV
VSLVADENPFAQGALRSEDCFILDHGKDGKIFVWKGKQANMEERKAALKT
ASDFISKMDYPKQTQVSVLPEGGETPLFRQFFKNWRDPDQTEGLGLAYLS
SHIAHVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRVEGSNKVPVD
PATYGQFYGGDSYIILYNYRHGSRQGQIIYNWQGAQSTQDEVAASAILTA
QLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIVYKGGTSREGGQTAPA
STRLFQVRASSSGATRAVEIIPKAGALNSNDAFVLKTPSAAYLWVGAGAS
EAEKTGAQELLRVLRAQPVQVAEGSEPDSFWEALGGKATYRTSPRLKDKK
MDAHPPRLFACSNKIGRFVIEEVPGEFMQEDLATDDVMLLDTWDQVFVWV
GKDSQDEEKTEALTSAKRYIDTDPAHRDRRTPITVVKQGFEPPSFVGWFL
GWDDSYWSVDPLDRALAELAA
3D structure
PDB2fgh The structure of gelsolin bound to ATP
ChainB
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP B R363 N368 W369 R370 D371 K503 R542 R629 L630 R329 N334 W335 R336 D337 K469 R508 R595 L596
Gene Ontology
Molecular Function
GO:0003779 actin binding
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0046872 metal ion binding
GO:0051015 actin filament binding
Biological Process
GO:0007417 central nervous system development
GO:0008154 actin polymerization or depolymerization
GO:0030030 cell projection organization
GO:0030031 cell projection assembly
GO:0051014 actin filament severing
GO:0051016 barbed-end actin filament capping
GO:0051693 actin filament capping
GO:0060271 cilium assembly
Cellular Component
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0015629 actin cytoskeleton

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2fgh, PDBe:2fgh, PDBj:2fgh
PDBsum2fgh
PubMed16469333
UniProtQ28372|GELS_HORSE Gelsolin (Gene Name=GSN)

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