Structure of PDB 2fge Chain B

Receptor sequence
>2fgeB (length=979) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
DEAEKLGFEKVSEEFISECKSKAILFKHKKTGCEVMSVSNEDENKVFGVV
FRTPPKDSTGIPHILQHSVLCGSRKYPVKEPFVELLKGSLHTFLNAFTYP
DRTCYPVASTNTKDFYNLVDVYLDAVFFPKCVDDAHTFQQEGWHYELNDP
SEDISYKGVVFNEMKGVYSQPDNILGRIAQQALSPENTYGVDSGGDPKDI
PNLTFEEFKEFHRQYYHPSNARIWFYGDDDPVHRLRVLSEYLDMFEASPS
PNSSKIKFQKLFSEPVRLVEKYPAGRDGDLKKKHMLCVNWLLSEKPLDLQ
TQLALGFLDHLMLGTPASPLRKILLESGLGEALVSSGLSDELLQPQFGIG
LKGVSEENVQKVEELIMDTLKKLAEEGFDNDAVEASMNTIEFSLRENNTG
SFPRGLSLMLQSISKWIYDMDPFEPLKYTEPLKALKTRIAEEGSKAVFSP
LIEKLILNNSHRVTIEMQPDPEKATQEEVEEKNILEKVKAAMTEEDLAEL
ARATEELKLKQETPDPPEALRCVPSLNLGDIPKEPTYVPTEVGDINGVKV
LRHDLFTNDIIYTEVVFDIGSLKHELLPLVPLFCQSLLEMGTKDLTFVQL
NQLIGRKTGGISVYPLTSSVRGKDEPCSKIIVRGKSMAGRADDLFNLMNC
LLQEVQFTDQQRFKQFVSQSRARMENRLRGSGHGIAAARMDAMLNIAGWM
SEQMGGLSYLEFLHTLEKKVDEDWEGISSSLEEIRRSLLARNGCIVNMTA
DGKSLTNVEKSVAKFLDLLPENPSGGLVTWDGRLPLRNEAIVIPTQVNYV
GKAGNIYSTGYELDGSAYVISKHISNTWLWDRVRVSGGAYGGFCDFDSHS
GVFSYLSYRDPNLLKTLDIYDGTGDFLRGLDVDQETLTKAIIGTIGDVDS
YQLPDAKGYSSLLRHLLGVTDEERQRKREEILTTSLKDFKDFAQAIDVVR
DKGVAVAVASAEDIDAANNERSNFFEVKK
3D structure
PDB2fge The closed structure of presequence protease PreP forms a unique 10 000 A(3) chamber for proteolysis
ChainB
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.24.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B Q80 H81 N109 A110 F111 T112 E155 M178 R848 Y854 Q66 H67 N95 A96 F97 T98 E141 M164 R834 Y840
BS02 ZN B H77 H81 E177 H63 H67 E163
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0005515 protein binding
GO:0008237 metallopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
GO:0016485 protein processing
Cellular Component
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0005829 cytosol
GO:0009507 chloroplast
GO:0009570 chloroplast stroma
GO:0009941 chloroplast envelope
GO:0048046 apoplast

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2fge, PDBe:2fge, PDBj:2fge
PDBsum2fge
PubMed16601675
UniProtQ9LJL3|PREP1_ARATH Presequence protease 1, chloroplastic/mitochondrial (Gene Name=PREP1)

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