Structure of PDB 2ffv Chain B

Receptor sequence
>2ffvB (length=481) Species: 9606 (Homo sapiens) [Search protein sequence]
LKVRWPDFNQEAYVGGFNQVESDKLRMDRAIPDTRHDQCQRKQWRVDLPA
TSVVITFHNEARSALLRTVVSVLKKSPPHLIKEIILVDDYSNDPEDGALL
GKIEKVRVLRNDRREGLMRSRVRGADAAQAKVLTFLDSHCECNEHWLEPL
LERVAEDRTRVVSPIIDVINMDNFQYVGASADLKGGFDWNLVFKWDYMTP
EQRRSRQGNPVAPIKTPMIAGGLFVMDKFYFEELGKYDMMMDVWGGENLE
ISFRVWQCGGSLEIIPCSRVGHVFRKQHPYTFPGGSGTVFARNTRRAAEV
WMDEYKNFYYAAVPSARNVPYGNIQSRLELRKKLSCKPFKWYLENVYPEL
RVPDHQDIAFGALQQGTNCLDTLGHFADGVVGVYECHNGNQEWALTKEKS
VKHMDLCLTVVDRAPGSLIKLQGCRENDSRQKWEQIEGNSKLRHVGSNLC
LDSRTAKSGGLSVEVCGPALSQQWKFTLNLQ
3D structure
PDB2ffv Dynamic Association between the Catalytic and Lectin Domains of Human UDP-GalNAc:Polypeptide {alpha}-N-Acetylgalactosaminyltransferase-2
ChainB
Resolution2.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.41: polypeptide N-acetylgalactosaminyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN B D224 H226 H359 D137 H139 H272
BS02 UDP B T143 F144 D176 R201 L204 D224 H226 V330 R362 H365 T56 F57 D89 R114 L117 D137 H139 V243 R275 H278
External links
PDB RCSB:2ffv, PDBe:2ffv, PDBj:2ffv
PDBsum2ffv
PubMed16434399
UniProtQ10471|GALT2_HUMAN Polypeptide N-acetylgalactosaminyltransferase 2 (Gene Name=GALNT2)

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