Structure of PDB 2f64 Chain B

Receptor sequence
>2f64B (length=158) Species: 5691 (Trypanosoma brucei) [Search protein sequence]
HHHHHHMRKIYIAGPAVFNPDMGASYYNKVRELLKKENVMPLIPTDNEAT
EALDIRQKNIQMIKDCDAVIADLSPFRGHEPDCGTAFEVGCAAALNKMVL
TFTSDRRNMREKYGSGVDKDNLRVEGFGLPFNLMLYDGVEVFDSFESAFK
YFLANFPS
3D structure
PDB2f64 Using fragment cocktail crystallography to assist inhibitor design of Trypanosoma brucei nucleoside 2-deoxyribosyltransferase.
ChainB
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.2.6: nucleoside deoxyribosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 12Q B E127 N134 L135 M136 E125 N132 L133 M134
BS02 12Q B V19 P46 T47 E50 I57 V17 P44 T45 E48 I55
Gene Ontology
Molecular Function
GO:0070694 deoxyribonucleoside 5'-monophosphate N-glycosidase activity
Biological Process
GO:0009159 deoxyribonucleoside monophosphate catabolic process
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2f64, PDBe:2f64, PDBj:2f64
PDBsum2f64
PubMed17004709
UniProtQ57VC7

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