Structure of PDB 2enx Chain B

Receptor sequence
>2enxB (length=310) Species: 205921 (Streptococcus agalactiae A909) [Search protein sequence]
SKILVFGHQNPDSDAIGSSVAFAYLAKEAWGLDTEAVALGTPNEETAYVL
DYFGVQAPRVVESAKAEGVETVILTDHNEFQQSISDIKDVTVYGVVDHHR
VANFETANPLYMRLEPVGSASSIVYRMFKENGVSVPKELAGLLLSGLISD
TLLLKSPTTHASDIPVAKELAELAGVNLEEYGLEMLKAGTNLSSKTAAEL
IDIDAKTFELNGEAVRVAQVNTVDINDILARQEEIEVAIQEAIVTEGYSD
FVLMITDIVNSNSEILALGSNMAKVEAAFEFTLENNHAFLAGAVSRKKQV
VPQLTESYNA
3D structure
PDB2enx Structure of the Streptococcus agalactiae family II inorganic pyrophosphatase at 2.80 A resolution
ChainB
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.1: inorganic diphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN B H9 D13 D77 H8 D12 D76
BS02 MN B D15 D77 H99 D151 D14 D76 H98 D150
BS03 2PN B D13 H99 H100 D151 K207 R297 K298 D12 H98 H99 D150 K206 R296 K297
BS04 TRP B W31 Y112 M128 W30 Y111 M127
Gene Ontology
Molecular Function
GO:0004427 inorganic diphosphate phosphatase activity
GO:0016462 pyrophosphatase activity
GO:0016787 hydrolase activity
GO:0030145 manganese ion binding
GO:0046872 metal ion binding
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:2enx, PDBe:2enx, PDBj:2enx
PDBsum2enx
PubMed17505113
UniProtQ3K0B5|PPAC_STRA1 Probable manganese-dependent inorganic pyrophosphatase (Gene Name=ppaC)

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