Structure of PDB 2el9 Chain B

Receptor sequence
>2el9B (length=376) Species: 562 (Escherichia coli) [Search protein sequence]
NIQAIRGMNDYLPGETAIWQRIEGTLKNVLGSYGYSEIRLPIVEQTPLFK
RAIGEVTDVVEKEMYTFEDRNGDSLTLRPEGTAGCVRAGIEHGLLYNQEQ
RLWYIGPMFRHERPQKGRYRQFHQLGCEVFGLQGPDIDAELIMLTARWWR
ALGISEHVTLELNSIGSLEARANYRALGDYLDEESREHFAGLCKLLESAG
IAYTVNQRLVRGLDYYNRTVFEWVTNSLGSQGTVCAGGRYDGLVEQLGGR
ATPAVGFAMGLERLVLLVQAVNPEFKADPVVDIYLVASGADTQSAAMALA
ERLRDELPGVKLMTNHGGGNFKKQFARADKWGARVAVVLGESEVANGTAV
VKDLRSGEQTAVAQDSVAAHLRTLLG
3D structure
PDB2el9 Crystal structure of E.coli Histidyl-tRNA synthetase complexed with a histidyl-adenylate analogue
ChainB
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.1.1.21: histidine--tRNA ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HSS B E83 T85 R113 G120 R121 Y122 F125 Q127 E131 R259 Y263 Y264 V282 Y288 G304 F305 A306 G308 R311 E80 T82 R110 G117 R118 Y119 F122 Q124 E128 R211 Y215 Y216 V234 Y240 G256 F257 A258 G260 R263
Gene Ontology
Molecular Function
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004821 histidine-tRNA ligase activity
GO:0005524 ATP binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0006412 translation
GO:0006427 histidyl-tRNA aminoacylation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:2el9, PDBe:2el9, PDBj:2el9
PDBsum2el9
PubMed
UniProtP60906|SYH_ECOLI Histidine--tRNA ligase (Gene Name=hisS)

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