Structure of PDB 2eb0 Chain B

Receptor sequence
>2eb0B (length=307) Species: 243232 (Methanocaldococcus jannaschii DSM 2661) [Search protein sequence]
MRYVVGHKNPDTDSIASAIVLAYFLDCYPARLGDINPETEFVLRKFGVME
PELIESAKGKEIILVDHSEKSQSFDDLEEGKLIAIIDHHKVGLTTTEPIL
YYAKPVGSTATVIAELYFKDAIDLIGGKKKELKPDLAGLLLSAIISDTVL
FKSPTTTDLDKEMAKKLAEIAGISNIEEFGMEILKAKSVVGKLKPEEIIN
MDFKNFDFNGKKVGIGQVEVIDVSEVESKKEDIYKLLEEKLKNEGYDLIV
FLITDIMKEGSEALVVGNKEMFEKAFNVKVEGNSVFLEGVMSRKKQVVPP
LERAYNG
3D structure
PDB2eb0 Crystal structure of Methanococcus jannaschii inorganic pyrophosphatase
ChainB
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.1: inorganic diphosphatase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MN B D13 D66 H88 D147 D13 D66 H88 D147
BS02 MN B H7 D11 D66 H7 D11 D66
Gene Ontology
Molecular Function
GO:0004427 inorganic diphosphate phosphatase activity
GO:0016462 pyrophosphatase activity
GO:0016787 hydrolase activity
GO:0030145 manganese ion binding
GO:0046872 metal ion binding
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:2eb0, PDBe:2eb0, PDBj:2eb0
PDBsum2eb0
PubMed
UniProtQ58025|PPAC_METJA Manganese-dependent inorganic pyrophosphatase (Gene Name=ppaC)

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