Structure of PDB 2e41 Chain B

Receptor sequence
>2e41B (length=232) Species: 70601 (Pyrococcus horikoshii OT3) [Search protein sequence]
MLGLKTSIIGRRVIYFQEITSTNEFAKTSYLEEGTVIVADKQTMGHGALN
RKWESPEGGLWLSIVLSPKVPQKDLPKIVFLGAVGVVETLKEFSIDGRIK
WPNDVLVNYKAIAGVLVEGKGDKIVLGIGLNVNNKVPNGATSMKLELGSE
VPLLSVFRSLITNLDRLYLNFLKNPMDILNLVRDNMILGVRVKILGDGSF
EGIAEDIDDFGRLIIRLDSGEVKKVIYGDVSL
3D structure
PDB2e41 Protein biotinylation visualized by a complex structure of biotin protein ligase with a substrate
ChainB
Resolution1.75 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) A48 A111
Catalytic site (residue number reindexed from 1) A48 A111
Enzyme Commision number 6.3.4.15: biotin--[biotin carboxyl-carrier protein] ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BTX B S21 T22 N23 Q42 G45 H46 G47 A48 R51 K52 W53 E54 L62 N103 G114 I128 G129 N131 P137 S21 T22 N23 Q42 G45 H46 G47 A48 R51 K52 W53 E54 L62 N103 G114 I128 G129 N131 P137
Gene Ontology
Molecular Function
GO:0004077 biotin--[biotin carboxyl-carrier protein] ligase activity
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0036211 protein modification process
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:2e41, PDBe:2e41, PDBj:2e41
PDBsum2e41
PubMed18372281
UniProtO57883

[Back to BioLiP]