Structure of PDB 2e3p Chain B

Receptor sequence
>2e3pB (length=231) Species: 9606 (Homo sapiens) [Search protein sequence]
HRFVQKVEEMVQNHMTYSLQDVGGDANWQLVVEEGEMKVYRREVEENGIV
LDPLKATHAVKGVTGHEVCNYFWNVDVRNDWETTIENFHVVETLADNAII
IYQTHKRVWPASQRDVLYLSVIRKIPALTENDPETWIVCNFSVDHDSAPL
NNRCVRAKINVAMICQTLVSPPQEISRDNILCKITYVANVNPGGWAPASV
LRAVAKREYPKFLKRFTSYVQEKTAGKPILF
3D structure
PDB2e3p Structural basis for specific lipid recognition by CERT responsible for nonvesicular trafficking of ceramide.
ChainB
Resolution1.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 16C B E446 H469 V472 A475 R478 N504 Y553 L568 Y576 F579 E82 H105 V108 A111 R114 N140 Y186 L201 Y209 F212
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:2e3p, PDBe:2e3p, PDBj:2e3p
PDBsum2e3p
PubMed18184806
UniProtQ9Y5P4|CERT_HUMAN Ceramide transfer protein (Gene Name=CERT1)

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