Structure of PDB 2e0n Chain B

Receptor sequence
>2e0nB (length=238) Species: 1097 (Chlorobaculum tepidum) [Search protein sequence]
SIISVSLGPGDPGLITVKALSQLREADVIYYPGTVSASGAVTSVALDILK
EFDLDPSKLRGMLVPMSRGAAEASYAANYASMAEEVQAGRRVAVVSVGDG
GFYSTASAIIERARRDGLDCSMTPGIPAFIAAGSAAGMPLALQSDSVLVL
AQIDEIGELERALVTHSTVVVMKLSTVRDELVSFLERYAKPFLYAEKVGM
AGEFITMEVDALRSRAIPYFSLLVCSPHCRQSTLSPFA
3D structure
PDB2e0n Crystal structures of CbiL, a methyltransferase involved in anaerobic vitamin B biosynthesis, and CbiL in complex with S-adenosylhomocysteine--implications for the reaction mechanism.
ChainB
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) P37 K63 V176
Catalytic site (residue number reindexed from 1) P32 K58 V169
Enzyme Commision number 2.1.1.130: precorrin-2 C(20)-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH B V104 G105 D106 F109 Y110 P134 A135 M179 K180 K204 V205 Y226 F227 S228 V97 G98 D99 F102 Y103 P127 A128 M172 K173 K197 V198 Y219 F220 S221
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
GO:0030788 precorrin-2 C20-methyltransferase activity
Biological Process
GO:0009236 cobalamin biosynthetic process
GO:0032259 methylation

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Molecular Function
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Biological Process
External links
PDB RCSB:2e0n, PDBe:2e0n, PDBj:2e0n
PDBsum2e0n
PubMed17229157
UniProtQ8KFD9

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