Structure of PDB 2dt5 Chain B

Receptor sequence
>2dt5B (length=211) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MKVPEAAISRLITYLRILEELEAQGVHRTSSEQLGGLAQVTAFQVRKDLS
YFGSYGTRGVGYTVPVLKRELRHILGLNRKWGLCIVGMGRLGSALADYPG
FGESFELRGFFDVDPEKVGRPVRGGVIEHVDLLPQRVPGRIEIALLTVPR
EAAQKAADLLVAAGIKGILNFAPVVLEVPKEVAVENVDFLAGLTRLSFAI
LNPKWREEMMG
3D structure
PDB2dt5 Crystal structure of TTHA1657 (AT-rich DNA-binding protein; p25) from Thermus thermophilus HB8 at 2.16 A resolution
ChainB
Resolution2.16 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 NAD B A94 Y98 F189 A94 Y98 F189
BS02 NAD B G87 G89 R90 L91 D112 V113 T147 V148 P149 F171 A172 P173 V187 F189 G87 G89 R90 L91 D112 V113 T147 V148 P149 F171 A172 P173 V187 F189
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0045892 negative regulation of DNA-templated transcription
GO:0051775 response to redox state
Cellular Component
GO:0005737 cytoplasm

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Biological Process

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Cellular Component
External links
PDB RCSB:2dt5, PDBe:2dt5, PDBj:2dt5
PDBsum2dt5
PubMed17154156
UniProtQ5SHS3|REX_THET8 Redox-sensing transcriptional repressor Rex (Gene Name=rex)

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