Structure of PDB 2dko Chain B

Receptor sequence
>2dkoB (length=103) Species: 9606 (Homo sapiens) [Search protein sequence]
ASGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLK
QYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELY
FYH
3D structure
PDB2dko Extended Substrate Recognition in Caspase-3 Revealed by High Resolution X-ray Structure Analysis
ChainB
Resolution1.06 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.22.56: caspase-3.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B Y204 S205 W206 R207 S249 F250 Y30 S31 W32 R33 S75 F76
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:2dko, PDBe:2dko, PDBj:2dko
PDBsum2dko
PubMed16787777
UniProtP42574|CASP3_HUMAN Caspase-3 (Gene Name=CASP3)

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