Structure of PDB 2d4i Chain B

Receptor sequence

>2d4iB (length=129) Species: 9031 (Gallus gallus)

KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGS
TDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVS
DGNGMNAWVAWRNRCKGTDVQAWIRGCRL

3D structure

• PDB: 2d4i Structural phase transition of monoclinic crystals of hen egg-white lysozyme
• Chain: B
• Resolution: 1.16 Å

Enzymatic activity

• Catalytic site (original residue number in PDB): E235 N246 D248 S250 D252 N259
• Catalytic site (residue number reindexed from 1): E35 N46 D48 S50 D52 N59
• Enzyme Commision number: 3.2.1.17: lysozyme.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	NO3	B	N265 N274 I278 P279	N65 N74 I78 P79
BS02	NO3	B	D266 R268 S281	D66 R68 S81
BS03	NO3	B	N265 D266 G267 T269 S272 R273	N65 D66 G67 T69 S72 R73
BS04	NA	B	S260 R261 C264 N265 R273	S60 R61 C64 N65 R73

Gene Ontology

Molecular Function

• GO:0003796 lysozyme activity
• GO:0005515 protein binding
• GO:0016231 beta-N-acetylglucosaminidase activity
• GO:0016798 hydrolase activity, acting on glycosyl bonds
• GO:0042802 identical protein binding

Biological Process

• GO:0016998 cell wall macromolecule catabolic process
• GO:0031640 killing of cells of another organism
• GO:0042742 defense response to bacterium
• GO:0050829 defense response to Gram-negative bacterium
• GO:0050830 defense response to Gram-positive bacterium

Cellular Component

• GO:0005576 extracellular region
• GO:0005615 extracellular space
• GO:0005737 cytoplasm
• GO:0005783 endoplasmic reticulum

External links

• PDB: RCSB:2d4i, PDBe:2d4i, PDBj:2d4i
• PDBsum: 2d4i
• PubMed: 16552138
• UniProt: P00698|LYSC_CHICK Lysozyme C (Gene Name=LYZ)