Structure of PDB 2cnw Chain B

Receptor sequence
>2cnwB (length=290) Species: 271 (Thermus aquaticus) [Search protein sequence]
QLSARLQEAIGRLRGRGRITEEDLKATLREIRRALMDADVNLEVARDFVE
RVREEALGKQVLESLTPAEVILATVYEALKEALGGEARLPVLKDRNLWFL
VGLQGSGKTTTAAKLALYYKGKGRRPLLVAADTQRPAAREQLRLLGEKVG
VPVLEVMDGESPESIRRRVEEKARLEARDLILVDTAGRLQIDEPLMGELA
RLKEVLGPDEVLLVLDAMTGQEALSVARAFDEKVGVTGLVLTKLDGDARG
GAALSARHVTGKPIYFAGVSEKPEGLEPFYPERLAGRILG
3D structure
PDB2cnw Structure of a Gdp:Alf(4) Complex of the Srp Gtpases Ffh and Ftsy, and Identification of a Peripheral Nucleotide Interaction Site.
ChainB
Resolution2.39 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.4: signal-recognition-particle GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP B G108 G110 K111 T112 T113 R138 K246 D248 G271 S273 E274 G105 G107 K108 T109 T110 R135 K243 D245 G268 S270 E271
BS02 ALF B Q107 G108 K111 R138 G190 Q104 G105 K108 R135 G187
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
Cellular Component
GO:0048500 signal recognition particle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2cnw, PDBe:2cnw, PDBj:2cnw
PDBsum2cnw
PubMed16780874
UniProtO07347|SRP54_THEAQ Signal recognition particle protein (Gene Name=ffh)

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