Structure of PDB 2cl8 Chain B

Receptor sequence
>2cl8B (length=128) Species: 10090 (Mus musculus) [Search protein sequence]
QSCLPNWIMHGKSCYLFSFSGNSWYGSKRHCSQLGAHLLKIDNSKEFEFI
ESQTSSHRINAFWIGLSRNQSEGPWFWEDGSAFFPNSFQVRNAVPQESLL
HNCVWIHGSEVYNQICNTSSYSICEKEL
3D structure
PDB2cl8 Structure of the Fungal Beta-Glucan-Binding Immune Receptor Dectin-1: Implications for Function.
ChainB
Resolution2.8 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BGC B E243 L244 E127 L128
BS02 CA B K156 D158 E162 E241 K40 D42 E46 E125
Gene Ontology
Molecular Function
GO:0001872 (1->3)-beta-D-glucan binding
Biological Process
GO:0071226 cellular response to molecule of fungal origin

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:2cl8, PDBe:2cl8, PDBj:2cl8
PDBsum2cl8
PubMed17473009
UniProtQ6QLQ4|CLC7A_MOUSE C-type lectin domain family 7 member A (Gene Name=Clec7a)

[Back to BioLiP]