Structure of PDB 2cj9 Chain B

Receptor sequence
>2cj9B (length=493) Species: 269797 (Methanosarcina barkeri str. Fusaro) [Search protein sequence]
GSHMKLQFNLKAYFKTSADPTPAKDAIAALFEEANSTLLTRGAPEGQGAK
VTEWKLGEDRIELTLQSGRYVRVHDAIFRLRKQLAEALGIEVESFIIKVP
ADHELRMLKVPYIKSMENIEGGIQLELEVGEAEMKNRVPDRILTLLEEKI
EAAQYAEHWNLLWQREPMEHPFKEDPTQAMMKEGWLKRGSSRGQWIHGPQ
SARIFRTFEKIVLEELLEPLGYREMIFPKLVTWEVWMKSGHAKGVYPEIY
YVCPPQTRDPDYWEEVADYYKVTHEVPTKLIKEKIAEPIGGMCYAQCPPF
WMYVAGETLPNEEIPVKVFDRSGTSHRYESGGIHGIERVDEFHRIEIVWI
GTKEEVLKCAEELHDRYMHIFNDILDIEWRKARVTPWFMAQEGLLGLAEE
NTVGTTDYEACLPYRGPDGEWLEFQNVSINGDKYPKGFNVKLQSGDELWS
GCSGVGLERWAAVFLAQKGLDPANWPEEFRNRVGEMPKGIRFL
3D structure
PDB2cj9 Structure of the Unusual Seryl-tRNA Synthetase Reveals a Distinct Zinc-Dependent Mode of Substrate Recognition
ChainB
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.1.1.11: serine--tRNA ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B C306 E355 C461 C297 E346 C452
BS02 SSA B A304 R336 E338 V348 F351 R353 E355 W396 Q400 E432 F433 Q434 N435 G463 R468 A295 R327 E329 V339 F342 R344 E346 W387 Q391 E423 F424 Q425 N426 G454 R459
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004828 serine-tRNA ligase activity
GO:0005524 ATP binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006412 translation
GO:0006434 seryl-tRNA aminoacylation
GO:0016260 selenocysteine biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2cj9, PDBe:2cj9, PDBj:2cj9
PDBsum2cj9
PubMed16675947
UniProtQ46AN5|SYS2_METBF Type-2 serine--tRNA ligase (Gene Name=serS2)

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