Structure of PDB 2cex Chain B

Receptor sequence
>2cexB (length=305) Species: 727 (Haemophilus influenzae) [Search protein sequence]
DYDLKFGMNAGTSSNEYKAAEMFAKEVKEKSQGKIEISLYPSSQLGDDRA
MLKQLKDGSLDFTFAESARFQLFYPEAAVFALPYVISNYNVAQKALFDTE
FGKDLIKKMDKDLGVTLLSQAYNGTRQTTSNRAINSIADMKGLKLRVPNA
ATNLAYAKYVGASPTPMAFSEVYLALQTNAVDGQENPLAAVQAQKFYEVQ
KFLAMTNHILNDQLYLVSNETYKELPEDLQKVVKDAAENAAKYHTKLFVD
GEKDLVTFFEKQGVKITHPDLVPFKESMKPYYAEFVKQTGQKGESALKQI
EAINP
3D structure
PDB2cex Conservation of Structure and Mechanism in Primary and Secondary Transporters Exemplified by Siap, a Sialic Acid Binding Virulence Factor from Haemophilus Influenzae
ChainB
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DAN B N10 E67 R147 F170 N187 N9 E66 R146 F169 N186 MOAD: Kd=20uM
PDBbind-CN: -logKd/Ki=4.70,Kd=20uM
BS02 ZN B D2 D4 D1 D3
Gene Ontology
Biological Process
GO:0055085 transmembrane transport
Cellular Component
GO:0030288 outer membrane-bounded periplasmic space
GO:0042597 periplasmic space

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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:2cex, PDBe:2cex, PDBj:2cex
PDBsum2cex
PubMed16702222
UniProtP44542|SIAP_HAEIN Sialic acid-binding periplasmic protein SiaP (Gene Name=siaP)

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