Structure of PDB 2cci Chain B

Receptor sequence
>2cciB (length=258) Species: 9606 (Homo sapiens) [Search protein sequence]
VPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEE
YKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPE
VAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQP
ANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPE
SLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSKYHGVSLL
NPPETLNL
3D structure
PDB2cci The role of the phospho-CDK2/cyclin A recruitment site in substrate recognition.
ChainB
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B M210 W217 E220 E224 R250 L253 Q254 I270 E277 Y280 I281 T282 D283 T285 M36 W43 E46 E50 R76 L79 Q80 I96 E103 Y106 I107 T108 D109 T111
Gene Ontology
Molecular Function
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
Biological Process
GO:0044772 mitotic cell cycle phase transition

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Molecular Function
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Biological Process
External links
PDB RCSB:2cci, PDBe:2cci, PDBj:2cci
PDBsum2cci
PubMed16707497
UniProtP20248|CCNA2_HUMAN Cyclin-A2 (Gene Name=CCNA2)

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