Structure of PDB 2c5v Chain B

Receptor sequence
>2c5vB (length=258) Species: 9606 (Homo sapiens) [Search protein sequence]
VPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEE
YKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPE
VAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQP
ANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPE
SLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSKYHGVSLL
NPPETLNL
3D structure
PDB2c5v Differential Binding of Inhibitors to Active and Inactive Cdk2 Provides Insights for Drug Design.
ChainB
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B M210 W217 E220 R250 Q254 I281 T282 M36 W43 E46 R76 Q80 I107 T108
Gene Ontology
Molecular Function
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
Biological Process
GO:0044772 mitotic cell cycle phase transition

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Molecular Function
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Biological Process
External links
PDB RCSB:2c5v, PDBe:2c5v, PDBj:2c5v
PDBsum2c5v
PubMed16492568
UniProtP20248|CCNA2_HUMAN Cyclin-A2 (Gene Name=CCNA2)

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