Structure of PDB 2bve Chain B

Receptor sequence
>2bveB (length=118) Species: 10090 (Mus musculus) [Search protein sequence]
TWGVSSPKNVQGLSGSCLLIPCIFSYPADVPVSNGITAIWYYDYSGKRQV
VIHSGDPKLVDKRFRGRAELMGNMDHKVCNLLLKDLKPEDSGTYNFRFEI
SDSNRWLDVKGTTVTVTT
3D structure
PDB2bve Crystallographic and in Silico Analysis of the Sialoside-Binding Characteristics of the Siglec Sialoadhesin.
ChainB
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 PH5 B T117 T118 T117 T118 MOAD: ic50=215uM
BS02 PH5 B W2 R97 S103 R105 W106 L107 W2 R97 S103 R105 W106 L107 MOAD: ic50=215uM
External links
PDB RCSB:2bve, PDBe:2bve, PDBj:2bve
PDBsum2bve
PubMed17137591
UniProtQ62230|SN_MOUSE Sialoadhesin (Gene Name=Siglec1)

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