Structure of PDB 2bng Chain B

Receptor sequence
>2bngB (length=133) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
PETTEAIRAVEAFLNALQNEDFDTVDAALGDDLVYENVGFSRIRGGRRTA
TLLRRMQGRVGFEVKIHRIGADGAAVLTERTDALIIGPLRVQFWVCGVFE
VDDGRITLWRDYFDVYDMFKGLLRGLVALVVPS
3D structure
PDB2bng Structure of an Atypical Epoxide Hydrolase from Mycobacterium Tuberculosis Gives Insights Into its Function.
ChainB
Resolution2.5 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y46 N48 R91 D93 D122
Catalytic site (residue number reindexed from 1) Y35 N37 R80 D82 D111
Enzyme Commision number 3.3.2.10: soluble epoxide hydrolase.
3.3.2.11: cholesterol-5,6-oxide hydrolase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B E13 D114 E2 D103
Gene Ontology
Molecular Function
GO:0004301 epoxide hydrolase activity
GO:0016787 hydrolase activity
GO:0033963 cholesterol-5,6-oxide hydrolase activity
Biological Process
GO:0097176 epoxide metabolic process
Cellular Component
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2bng, PDBe:2bng, PDBj:2bng
PDBsum2bng
PubMed16051262
UniProtO33283|EPHG_MYCTU Epoxide hydrolase EphG (Gene Name=ephG)

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