Structure of PDB 2b9s Chain B

Receptor sequence
>2b9sB (length=52) Species: 5661 (Leishmania donovani) [Search protein sequence]
KAVSLGTSKINYIDPRIICSWAKAQDVPINKIFSATIQKKFPWAMNAENF
DF
3D structure
PDB2b9s The Structure of the Transition State of the Heterodimeric Topoisomerase I of Leishmania donovani as a Vanadate Complex with Nicked DNA.
ChainB
Resolution2.27 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.99.1.2: Transferred entry: 5.6.2.1.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B N221 Y222 N11 Y12
BS02 dna B S244 T246 S34 T36
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003917 DNA topoisomerase type I (single strand cut, ATP-independent) activity
Biological Process
GO:0006265 DNA topological change
Cellular Component
GO:0005694 chromosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2b9s, PDBe:2b9s, PDBj:2b9s
PDBsum2b9s
PubMed16487540
UniProtQ8WQM6

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