Structure of PDB 2b3r Chain B

Receptor sequence
>2b3rB (length=124) Species: 10090 (Mus musculus) [Search protein sequence]
GSGAVKLSVSYRNGTLFIMVMHIKDLVTEDGADPNPYVKTYLLPDTHKTS
KRKTKISRKTRNPTFNEMLVYSGYSKETLRQRELQLSVLSAESLRENFFL
GGITLPLKDFNLSKETVKWYQLTA
3D structure
PDB2b3r Crystal structure of the C2 domain of class II phosphatidylinositide 3-kinase C2alpha.
ChainB
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.137: phosphatidylinositol 3-kinase.
2.7.1.153: phosphatidylinositol-4,5-bisphosphate 3-kinase.
2.7.1.154: phosphatidylinositol-4-phosphate 3-kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SO4 B K1457 R1461 N1492 L1493 K76 R80 N111 L112
BS02 SO4 B Y1418 K1420 K1434 Y37 K39 K53
External links
PDB RCSB:2b3r, PDBe:2b3r, PDBj:2b3r
PDBsum2b3r
PubMed16338929
UniProtQ61194|P3C2A_MOUSE Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (Gene Name=Pik3c2a)

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