Structure of PDB 2ax4 Chain B

Receptor sequence
>2ax4B (length=195) Species: 9606 (Homo sapiens) [Search protein sequence]
HVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTISFALEEYLVSHAIPC
YSLDGDNVRHGLNRNLGFSPGDREENIRRIAEVAKLFADAGLVCITSFIS
PFAKDRENARKIHESAGLPFFEIFVDAPLNICESRDVKGLYKRARAGEIK
GFTGIDSDYEKPETPERVLKTNLSTVSDCVHQVVELLQEQNIVPY
3D structure
PDB2ax4 Crystal structure of the kinase domain of PAPSS 2
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.25: adenylyl-sulfate kinase.
2.7.7.4: sulfate adenylyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP B G62 G64 K65 T66 T67 R168 T204 V209 G29 G31 K32 T33 T34 R135 T171 V176
Gene Ontology
Molecular Function
GO:0004020 adenylylsulfate kinase activity
GO:0005524 ATP binding
Biological Process
GO:0000103 sulfate assimilation

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Molecular Function
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Biological Process
External links
PDB RCSB:2ax4, PDBe:2ax4, PDBj:2ax4
PDBsum2ax4
PubMed
UniProtO95340|PAPS2_HUMAN Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (Gene Name=PAPSS2)

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