Structure of PDB 2aqx Chain B

Receptor sequence
>2aqxB (length=287) Species: 10090 (Mus musculus) [Search protein sequence]
VQWSPFVMSFKKKYPWIQLAGHAGSFKAAANGRILKKHCESEQRCLDRLM
ADVLRPFVPAYHGDVVKDGERYNQMDDLLADFDSPCVMDCKMGVRTYLEE
ELTKARKKPSLRKDMYQKMVEVDPEAPTEEEKAQRAVTKPRYMQWRETIS
STATLGFRIEGIKKEDGSVNRDFKKTKTREQVTEAFREFTKGNQNILIAY
RDRLKAIRATLEISPFFKCHEVIGSSLLFIHDKKEQAKVWMIDFGKTTPL
PEGQTLQHDVPWQEGNREDGYLSGLDNLIDILTEMSQ
3D structure
PDB2aqx Structural insights into enzyme regulation for inositol 1,4,5-trisphosphate 3-kinase B
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG B K741 D893 K91 D243
BS02 ATP B W666 L669 A670 F676 K686 P709 M725 D726 L728 D739 K741 D893 W16 L19 A20 F26 K36 P59 M75 D76 L78 D89 K91 D243
Gene Ontology
Molecular Function
GO:0016301 kinase activity
Biological Process
GO:0032958 inositol phosphate biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:2aqx, PDBe:2aqx, PDBj:2aqx
PDBsum2aqx
PubMed16262249
UniProtB2RXC2

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