Structure of PDB 2aor Chain B

Receptor sequence
>2aorB (length=221) Species: 727 (Haemophilus influenzae) [Search protein sequence]
MIPQTLEQLLSQAQSIAGLTFGELADELHIPVPIDLKRDKGWVGMLLERA
LGATAGSKAEQDFSHLGVELKTLPINAEGYPLETTFVSLAPLVQNSGVKW
ENSHVRHKLSCVLWMPIEGSRHIPLRERHIGAPIFWKPTAEQERQLKQDW
EELMDLIVLGKLDQITARIGEVMQLRPKGANSRAVTKGIGKNGEIIDTLP
LGFYLRKEFTAQILNAFLETK
3D structure
PDB2aor MutH complexed with hemi- and unmethylated DNAs: coupling base recognition and DNA cleavage.
ChainB
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B K45 K48 G49 G52 M53 K66 T80 P82 E91 F94 K186 K37 K40 G41 G44 M45 K58 T72 P74 E83 F86 K178 PDBbind-CN: Kd=0.9uM
BS02 dna B R46 K48 T174 A175 R184 P185 G187 A188 N189 S190 R38 K40 T166 A167 R176 P177 G179 A180 N181 S182 PDBbind-CN: Kd=0.9uM
BS03 CA B D70 E77 L78 D62 E69 L70
BS04 CA B E56 D70 E48 D62
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004519 endonuclease activity
Biological Process
GO:0006281 DNA repair
GO:0006298 mismatch repair
GO:0006304 DNA modification
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2aor, PDBe:2aor, PDBj:2aor
PDBsum2aor
PubMed16209953
UniProtP44688|MUTH_HAEIN DNA mismatch repair protein MutH (Gene Name=mutH)

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