Structure of PDB 2acj Chain B

Receptor sequence
>2acjB (length=65) Species: 9606 (Homo sapiens) [Search protein sequence]
HMEQRILKFLEELGEGKATTAHDLSGKLGTPKKEINRVLYSLAKKGKLQK
EAGTPPLWKIAVSTQ
3D structure
PDB2acj Crystal structure of a junction between B-DNA and Z-DNA reveals two extruded bases.
ChainB
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.4.37: double-stranded RNA adenine deaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B K169 K170 N173 R174 Y177 T191 P192 P193 K32 K33 N36 R37 Y40 T54 P55 P56
BS02 dna B H159 K187 H22 K50
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003726 double-stranded RNA adenosine deaminase activity

View graph for
Molecular Function
External links
PDB RCSB:2acj, PDBe:2acj, PDBj:2acj
PDBsum2acj
PubMed16237447
UniProtP55265|DSRAD_HUMAN Double-stranded RNA-specific adenosine deaminase (Gene Name=ADAR)

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