Structure of PDB 2abi Chain B

Receptor sequence
>2abiB (length=234) Species: 9606 (Homo sapiens) [Search protein sequence]
SPVMVLENIEPEIVYAGYDDTAENLLSTLNRLAGKQMIQVVKWAKVLPGF
KNLPLEDQITLIQYSWMCLSSFALSWRSYKHTNSQFLYFAPDLVFNEEKM
HQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLSTIPKDGLKSQA
AFEEMRTNYIKELRKMVTSWQRFYQLTKLLDSMHDLVSDLLEFCFYTFRE
SHALKVEFPAMLVEIISDQLPKVESGNAKPLYFH
3D structure
PDB2abi Crystal structure of the human mineralocorticoid receptor ligand-binding domain bound to deoxycorticosterone
ChainB
Resolution2.33 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 1CA B L769 N770 A773 Q776 M807 S810 F829 M852 C942 T945 L29 N30 A33 Q36 M67 S70 F89 M112 C194 T197
External links
PDB RCSB:2abi, PDBe:2abi, PDBj:2abi
PDBsum2abi
PubMed
UniProtP08235|MCR_HUMAN Mineralocorticoid receptor (Gene Name=NR3C2)

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