Structure of PDB 2aax Chain B

Receptor sequence
>2aaxB (length=257) Species: 9606 (Homo sapiens) [Search protein sequence]
LVPQLSTISRALTPSPVMVLENIEPEIVYAGYDSSKPDTAENLLSTLNRL
AGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMSLLSFALSWRSYKHT
NSQFLYFAPDLVFNEEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIM
KVLLLLSTIPKDGLKSQAAFEEMRTNYIKELRKMVTNNSGQSWQRFYQLT
KLLDSMHDLVSDLLEFCFYTFRESHALKVEFPAMLVEIISDQLPKVESGN
AKPLYFH
3D structure
PDB2aax A Ligand-mediated Hydrogen Bond Network Required for the Activation of the Mineralocorticoid Receptor
ChainB
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PDN B L769 N770 A773 Q776 M807 L810 F829 M845 M852 C942 T945 L47 N48 A51 Q54 M85 L88 F107 M123 M130 C217 T220
External links
PDB RCSB:2aax, PDBe:2aax, PDBj:2aax
PDBsum2aax
PubMed15967794
UniProtP08235|MCR_HUMAN Mineralocorticoid receptor (Gene Name=NR3C2)

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