Structure of PDB 2a6i Chain B

Receptor sequence

>2a6iB (length=219) Species: 10090 (Mus musculus) [Search protein sequence]

EVQLQQSGAELVRAGSSVKMSCKASGYTFTSYGINWVKQRPGQGLEWIGY
INPGNGYTKYNEKFKGKTTLTVDKSSSTAYMQLRSLTSEDSAVYFCARSV
YYGGSYYFDYWGQGTTLTVSSAKTTPPSVYPLAPGSANSMVTLGCLVKGY
FPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSPRPSETVTC
NVAHPASSTKVDKKIVPRD

3D structure

PDB

2a6i Differential epitope positioning within the germline antibody paratope enhances promiscuity in the primary immune response.

Chain

Resolution

2.5 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	B	S31 Y32 G33 N35 Y50 S99 V100 Y101 Y102 G103 G104 Y106 Y107	S31 Y32 G33 N35 Y50 S99 V100 Y101 Y102 G103 G104 Y106 Y107

External links

PDB	RCSB:2a6i, PDBe:2a6i, PDBj:2a6i
PDBsum	2a6i
PubMed	16618601

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