Structure of PDB 1zz7 Chain B

Receptor sequence
>1zz7B (length=174) Species: 43759 (Streptomyces wedmorensis) [Search protein sequence]
ASTGFAELLKDRREQVKMDHAALASLLGETPETVAAWENGEGGELTLTQL
GRIAHVLGTSIGALTPPAGNDLDDGVIIQMPYVYNCLVRTKRAPSLVPLV
VDVLTDNPDDAKFNSGHAGNEFLFVLEGEIHMKWGNPKEALLPTGASMFV
EEHVPHAFTAAKGTGSAKLIAVNF
3D structure
PDB1zz7 Structural insight into antibiotic fosfomycin biosynthesis by a mononuclear iron enzyme
ChainB
Resolution2.1 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 1.11.1.23: (S)-2-hydroxypropylphosphonic acid epoxidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE2 B H138 E142 H180 H117 E121 H156
BS02 S0H B N135 H138 E142 H180 F182 N114 H117 E121 H156 F158
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0008198 ferrous iron binding
GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
GO:0046872 metal ion binding
GO:0051213 dioxygenase activity
Biological Process
GO:0017000 antibiotic biosynthetic process
GO:0051289 protein homotetramerization
GO:1901766 phosphinothricin biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1zz7, PDBe:1zz7, PDBj:1zz7
PDBsum1zz7
PubMed16015285
UniProtQ56185|HPPE_STRWE (S)-2-hydroxypropylphosphonic acid epoxidase (Gene Name=hppE)

[Back to BioLiP]