Structure of PDB 1zy0 Chain B

Receptor sequence
>1zy0B (length=191) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
DLPEIVASGDPVLHEKAREVDPGEIGSERIQKIIDDMIKVMRLAPGVGLA
APQIGVPLRIIVLEDTKEYISYAPKEEILAQERRHFDLMVMVNPVLKERS
NKKALFFEGCLSVDGFRAAVERYLEVVVTGYDRQGKRIEVNASGWQARIL
QHECDHLDGNLYVDKMVPRTFRTVDNLDLPLAEGCPKLGSH
3D structure
PDB1zy0 The crystal structure of mitochondrial (Type 1A) peptide deformylase provides clear guidelines for the design of inhibitors specific for the bacterial forms
ChainB
Resolution2.9 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) G49 Q54 C111 L112 H153 E154 H157
Catalytic site (residue number reindexed from 1) G48 Q53 C110 L111 H152 E153 H156
Enzyme Commision number 3.5.1.88: peptide deformylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B C111 H153 H157 C110 H152 H156
Gene Ontology
Molecular Function
GO:0042586 peptide deformylase activity

View graph for
Molecular Function
External links
PDB RCSB:1zy0, PDBe:1zy0, PDBj:1zy0
PDBsum1zy0
PubMed16192279
UniProtQ9FV53|DEF1A_ARATH Peptide deformylase 1A, chloroplastic/mitochondrial (Gene Name=PDF1A)

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