Structure of PDB 1zh1 Chain B

Receptor sequence
>1zh1B (length=163) [Search protein sequence]
FFSCQRGYKGVWRGDGIMQTTCPCGAQITGHVKNGSMRIVGPRTCSNTWH
GTFPINAYTTGPCTPSPAPNYSRALWRVAAEEYVEVTRVGDFHYVTGMTT
DNVKCPCQVPAPEFFTEVDGVRLHRYAPACKPLLREEVTFLVGLNQYLVG
SQLPCEPEPDVAV
3D structure
PDB1zh1 Structure of the zinc-binding domain of an essential component of the hepatitis C virus replicase.
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.21.98: hepacivirin.
3.4.22.-
3.6.1.15: nucleoside-triphosphate phosphatase.
3.6.4.13: RNA helicase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN B C39 C57 C59 C80 C4 C22 C24 C45
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:1zh1, PDBe:1zh1, PDBj:1zh1
PDBsum1zh1
PubMed15902263
UniProtQ9WMX2|POLG_HCVCO Genome polyprotein

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