Structure of PDB 1zco Chain B

Receptor sequence
>1zcoB (length=262) Species: 2261 (Pyrococcus furiosus) [Search protein sequence]
MKYSKEYDEKTVVKINDVKFGEGFTIIAGPCSIESREQIMKVAEFLAEVG
IKVLRGGAFKPRTSPYSFQGYGEKALRWMREAADEYGLVTVTEVMDTRHV
ELVAKYSDILQIGARNSQNFELLKEVGKVENPVLLKRGMGNTIQELLYSA
EYIMAQGNENVILCERGIRTFETATRFTLDISAVPVVKELSHLPIIVDPS
HPAGRRSLVIPLAKAAYAIGADGIMVEVHPEPEKALSDSQQQLTFDDFLQ
LLKELEALGWKG
3D structure
PDB1zco Substrate Ambiguity and Crystal Structure of Pyrococcus furiosus 3-Deoxy-d-arabino-heptulosonate-7-phosphate Synthase: An Ancestral 3-Deoxyald-2-ulosonate-phosphate Synthase?(,)
ChainB
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.54: 3-deoxy-7-phosphoheptulonate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN B C31 H201 E227 D238 C31 H201 E227 D238
BS02 PEP B R55 K60 Q111 A114 K136 R166 H201 R55 K60 Q111 A114 K136 R166 H201
Gene Ontology
Molecular Function
GO:0003849 3-deoxy-7-phosphoheptulonate synthase activity
GO:0016740 transferase activity
GO:0016832 aldehyde-lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0009058 biosynthetic process
GO:0009073 aromatic amino acid family biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:1zco, PDBe:1zco, PDBj:1zco
PDBsum1zco
PubMed16142893
UniProtQ8U0A9

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