Structure of PDB 1z6t Chain B

Receptor sequence
>1z6tB (length=586) Species: 9606 (Homo sapiens) [Search protein sequence]
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQ
QRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDGIPVVSSSSGK
DSVSGITSYVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWV
TIHGMAGCGKSVLAAEAVRDHSLLEGCFPGGVHWVSVGKQDKSGLLMKLQ
NLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWV
LKAFDSQCQILLTTRDKSVTDSVMGPKYVVPVESSLGKEKGLEILSLFVN
MKKADLPEQAHSIIKECKGSPLVVSLIGALLRDFPNRWEYYLKQLQNKQF
KRIRKSSSYDYEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVL
CILWDMETEEVEDILQEFVNKSLLFCDRNGKSFRYYLHDLQVDFLTEKNC
SQLQDLHKKIITQFQRYHQPHTLSPDQEDCMYWYNFLAYHMASAKMHKEL
CALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKDCAVSENFQEFLSL
NGHLLGRQPFPNIVQLGLCEPETSEVYQQAKLQAKQ
3D structure
PDB1z6t Structure of the apoptotic protease-activating factor 1 bound to ADP
ChainB
Resolution2.21 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP B V125 F126 V127 G157 G159 K160 S161 V162 P321 L322 F425 H438 V125 F126 V127 G157 G159 K160 S161 V162 P321 L322 F425 H438
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

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Molecular Function
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Biological Process
External links
PDB RCSB:1z6t, PDBe:1z6t, PDBj:1z6t
PDBsum1z6t
PubMed15829969
UniProtO14727|APAF_HUMAN Apoptotic protease-activating factor 1 (Gene Name=APAF1)

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