Structure of PDB 1yf8 Chain B

Receptor sequence
>1yf8B (length=255) Species: 3972 (Viscum album) [Search protein sequence]
CSASEPTVRIVGRNGMNVDVRDDDFHDGNQIQLWPSKSNNDPNQLWTIKR
DGTIRSNGSCLTTYGYTAGVYVMIFDCNTAVREATIWQIWGNGTIINPRS
NLALAASSGIKGTTLTVQTLDYTLGQGWLAGNDTAPREVTIYGFNDLCME
SNGGSVWVETCVSQQNDRWALYGDGSIRPEQNQDQCLTSGRDSVAGINIV
SCSGGSSGQRWVFTNEGAILNLKNGLAMDVANPGLGQIIIYPATGKPNQM
WLPVP
3D structure
PDB1yf8 Crystal structure of himalayan mistletoe ribosome-inactivating protein reveals the presence of a natural inhibitor and a new functionally active sugar-binding site.
ChainB
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.2.22: rRNA N-glycosylase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 GAL B D229 Y241 N248 D229 Y241 N248
BS02 GAL B T63 M73 V81 A84 T63 M73 V81 A84
BS03 GAL B D19 R21 D22 Q32 W34 K37 D19 R21 D22 Q32 W34 K37
External links
PDB RCSB:1yf8, PDBe:1yf8, PDBj:1yf8
PDBsum1yf8
PubMed15774467
UniProtQ6ITZ3|ML4_VISAL Beta-galactoside-specific lectin 4

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