Structure of PDB 1xv9 Chain B

Receptor sequence
>1xv9B (length=246) Species: 9606 (Homo sapiens) [Search protein sequence]
PVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLA
PVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEIC
HIVLNTTFCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKL
QLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRR
PRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS
3D structure
PDB1xv9 A Structural Basis for Constitutive Activity in the Human CAR/RXRalpha Heterodimer.
ChainB
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B K177 R183 I191 K195 L342 E345 I346 K75 R81 I89 K93 L240 E243 I244
BS02 CI2 B F161 I164 N165 H203 Y224 F238 Y326 F59 I62 N63 H101 Y122 F136 Y224
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:1xv9, PDBe:1xv9, PDBj:1xv9
PDBsum1xv9
PubMed15610735
UniProtQ14994|NR1I3_HUMAN Nuclear receptor subfamily 1 group I member 3 (Gene Name=NR1I3)

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