Structure of PDB 1xnx Chain B

Receptor sequence
>1xnxB (length=232) Species: 10090 (Mus musculus) [Search protein sequence]
QKELVQILLGAHTRHVGPLFDQFVQFKPPAYLFMHHRPFQPRGPVLPLLT
HFADINTFMVQQIIKFTKDLPLFRSLTMEDQISLLKGAAVEILHISLNTT
FCLQTENFFCGPLCYKMEDAVHAGFQYEFLESILHFHKNLKGLHLQEPEY
VLMAATALFSPDRPGVTQREEIDQLQEEMALILNNHIMEQQSRLQSRFLY
AKLMGLLADLRSINNAYSYELQRLTPLLGEIC
3D structure
PDB1xnx Structure of the murine constitutive androstane receptor complexed to androstenol; a molecular basis for inverse agonism
ChainB
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATE B F171 N175 F227 M236 F52 N56 F108 M117 BindingDB: IC50=250nM
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:1xnx, PDBe:1xnx, PDBj:1xnx
PDBsum1xnx
PubMed15610734
UniProtO35627|NR1I3_MOUSE Nuclear receptor subfamily 1 group I member 3 (Gene Name=Nr1i3)

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