Structure of PDB 1x9i Chain B

Receptor sequence
>1x9iB (length=301) Species: 13773 (Pyrobaculum aerophilum) [Search protein sequence]
SQLLQDYLNWENYILRRVDFPTSYVVEGEVVRIEAMPRLYISGMGGSGVV
ADLIRDFSLTWNWEVEVIAVKDYFLKARDGLLIAVSYSGNTIETLYTVEY
AKRRRIPAVAITTGGRLAQMGVPTVIVPKASAPRAALPQLLTAALHVVAK
VYGIDVKIPEGLEPPNEALIHKLVEEFQKRPTIIAAESMRGVAYRVKNEF
NENAKIEPSVEILPEAHHNWIEGSERAVVALTSPHIPKEHQERVKATVEI
VGGSIYAVEMHPKGVLSFLRDVGIASVKLAEIRGVNPLATPRIDALKRRL
Q
3D structure
PDB1x9i Structural basis for phosphomannose isomerase activity in phosphoglucose isomerase from Pyrobaculum aerophilum: a subtle difference between distantly related enzymes.
ChainB
Resolution1.16 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R135 E203 H219 K298
Catalytic site (residue number reindexed from 1) R134 E202 H218 K297
Enzyme Commision number 5.3.1.8: mannose-6-phosphate isomerase.
5.3.1.9: glucose-6-phosphate isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 G6Q B G46 G47 S48 S87 Y88 S89 T92 P134 R135 E203 K298 G45 G46 S47 S86 Y87 S88 T91 P133 R134 E202 K297
Gene Ontology
Molecular Function
GO:0004347 glucose-6-phosphate isomerase activity
GO:0004476 mannose-6-phosphate isomerase activity
GO:0016853 isomerase activity
GO:0097367 carbohydrate derivative binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:1901135 carbohydrate derivative metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:1x9i, PDBe:1x9i, PDBj:1x9i
PDBsum1x9i
PubMed15518558
UniProtQ8ZWV0|PGMI_PYRAE Bifunctional phosphoglucose/phosphomannose isomerase (Gene Name=PAE1610)

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