Structure of PDB 1x14 Chain B

Receptor sequence
>1x14B (length=364) Species: 562 (Escherichia coli) [Search protein sequence]
HHHGRIGIPRERLTNETRVAATPKTVEQLLKLGFTVAVESGAGQLASFDD
KAFVQAGAEIVEGNSVWQSEIILKVNAPLDDEIALLNPGTTLVSFIWPAQ
NPELMQKLAERNVTVMAMDSVPRISRAQSLDALSSMANIAGYRAIVEAAH
EFGRFFTGQITAAGKVPPAKVMVIGAGVAGLAAIGAANSLGAIVRAFDTR
PEVKEQVQSMGAEFLELDMSDAFIKAEMELFAAQAKEVDIIVTTALIPGK
PAPKLITREMVDSMKAGSVIVDLAAQNGGNCEYTVPGEIFTTENGVKVIG
YTDLPGRLPTQSSQLYGTNLVNLLKLLCKEKDGNITVDFDDVVIRGVTVI
RAGEITWPAPPIQV
3D structure
PDB1x14 X-ray Structure of Domain I of the Proton-pumping Membrane Protein Transhydrogenase from Escherichia coli
ChainB
Resolution1.94 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R1015 N1073 F1092 W1094 D1116 R1120 Q1125 D1128 S1131 Q1287
Catalytic site (residue number reindexed from 1) R18 N76 F95 W97 D119 R123 Q128 D131 S134 Q276
Enzyme Commision number 7.1.1.1: proton-translocating NAD(P)(+) transhydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD B R1120 Q1125 G1174 V1175 D1195 R1197 E1238 A1256 L1257 L1266 R123 Q128 G177 V178 D198 R200 E227 A245 L246 L255
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
Biological Process
GO:1902600 proton transmembrane transport

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Molecular Function
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Biological Process
External links
PDB RCSB:1x14, PDBe:1x14, PDBj:1x14
PDBsum1x14
PubMed16083909
UniProtP07001|PNTA_ECOLI NAD(P) transhydrogenase subunit alpha (Gene Name=pntA)

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