Structure of PDB 1wwk Chain B

Receptor sequence
>1wwkB (length=302) Species: 70601 (Pyrococcus horikoshii OT3) [Search protein sequence]
MKVLVAAPLHEKAIQVLKDAGLEVIYEEYPDEDRLVELVKDVEAIIVRSK
PKVTRRVIESAPKLKVIARAGVGLDNIDVEAAKEKGIEVVNAPAASSRSV
AELAVGLMFSVARKIAFADRKMREGVWAKKEAMGIELEGKTIGIIGFGRI
GYQVAKIANALGMNILLYDPYPNEERAKEVNGKFVDLETLLKESDVVTIH
VPLVESTYHLINEERLKLMKKTAILINTSRGPVVDTNALVKALKEGWIAG
AGLDVFEEEPLPKDHPLTKFDNVVLTPHIGASTVEAQERAGVEVAEKVVK
IL
3D structure
PDB1wwk Crystal structure of phosphoglycerate dehydrogenase from Pyrococcus horikoshii OT3
ChainB
Resolution1.9 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S96 R230 D254 E259 H278
Catalytic site (residue number reindexed from 1) S96 R230 D254 E259 H278
Enzyme Commision number 1.1.1.95: phosphoglycerate dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD B V100 F147 G148 R149 I150 Y168 D169 P170 H200 V201 P202 T207 T228 S229 D254 H278 G280 V100 F147 G148 R149 I150 Y168 D169 P170 H200 V201 P202 T207 T228 S229 D254 H278 G280
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0051287 NAD binding

View graph for
Molecular Function
External links
PDB RCSB:1wwk, PDBe:1wwk, PDBj:1wwk
PDBsum1wwk
PubMed
UniProtO50095

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