Structure of PDB 1wbm Chain B

Receptor sequence

>1wbmB (length=99) Species: 11676 (Human immunodeficiency virus 1)

PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGI
GGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF

3D structure

• PDB: 1wbm Synthesis of Novel, Potent, Diol-Based HIV-1 Protease Inhibitors Via Intermolecular Pinacol Homocoupling of (2S)-2-Benzyloxymethyl-4-Phenylbutanal.
• Chain: B
• Resolution: 2.0 Å

Enzymatic activity

• Catalytic site (original residue number in PDB): D25 T26 G27
• Catalytic site (residue number reindexed from 1): D25 T26 G27

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	BLL	B	R8 D25 G27 A28 D29 D30 G48 G49 P81 V82 I84	R8 D25 G27 A28 D29 D30 G48 G49 P81 V82 I84

Gene Ontology

Molecular Function

• GO:0004190 aspartic-type endopeptidase activity

Biological Process

• GO:0006508 proteolysis

External links

• PDB: RCSB:1wbm, PDBe:1wbm, PDBj:1wbm
• PDBsum: 1wbm
• UniProt: Q8Q3H0