Structure of PDB 1v83 Chain B

Receptor sequence
>1v83B (length=241) Species: 9606 (Homo sapiens) [Search protein sequence]
ALPTIHVVTPTYSRPVQKAELTRMANTLLHVPNLHWLVVEDAPRRTPLTA
RLLRDTGLNYTHLHVETPRIPRGTMQRNLALRWLRETFPRNSSQPGVVYF
ADDDNTYSLELFEEMRSTRRVSVWPVAFVGGLRYEAPRVNGAGKVVRWKT
VFDPHRPFAIDMAGFAVNLRLILQRSQAYFKLRGVKGGYQESSLLRELVT
LNDLEPKAANCTKILVWHTRTEKPVLVNEGKKGFTDPSVEI
3D structure
PDB1v83 Structural Basis for Acceptor Substrate Recognition of a Human Glucuronyltransferase, GlcAT-P, an Enzyme Critical in the Biosynthesis of the Carbohydrate Epitope HNK-1
ChainB
Resolution1.9 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D197 E284
Catalytic site (residue number reindexed from 1) D104 E191
Enzyme Commision number 2.4.1.135: galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN B D197 R313 D104 R220
BS02 UDP B P91 T92 Y93 D122 R165 D195 D196 D197 H311 R313 P10 T11 Y12 D41 R72 D102 D103 D104 H218 R220
Gene Ontology
Molecular Function
GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:1v83, PDBe:1v83, PDBj:1v83
PDBsum1v83
PubMed14993226
UniProtQ9P2W7|B3GA1_HUMAN Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 (Gene Name=B3GAT1)

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