Structure of PDB 1uyr Chain B

Receptor sequence
>1uyrB (length=695) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
ATPYPVKEWLQPKRYKAHLMGTTYVYDFPELFRQASSSQWKNFSADVKLT
DDFFISNELIEDENGELTEVEREPGANAIGMVAFKITVKTPEYPRGRQFV
VVANDITFKIGSFGPQEDEFFNKVTEYARKRGIPRIYLAANSGARIGMAE
EIVPLFQVAWNDAANPDKGFQYLYLTSEGMETLKKFDKENSVLTERTVIN
GEERFVIKTIIGSEDGLGVECLRGSGLIAGATSRAYHDIFTITLVTCRSV
GIGAYLVRLGQRAIQVEGQPIILTGAPAINKMLGREVYTSNLQLGGTQIM
YNNGVSHLTAVDDLAGVEKIVEWMSYVPAKRNMPVPILETKDTWDRPVDF
TPTNDETYDVRWMIEGRETESGFEYGLFDKGSFFETLSGWAKGVVVGRAR
LGGIPLGVIGVETRTVENLIPADPANPNSAETLIQEPGQVWHPNSAFKTA
QAINDFNNGEQLPMMILANWRGFSGNEVLKYGSFIVDALVDYKQPIIIYI
PPTGELRGGSWVVVDPTINADQMEMYADVNARAGVLEPQGMVGIKFRREK
LLDTMNRELLPIYGQISLQFADLHDRSSRMVAKGVISKELEWTEARRFFF
WRLRRRLNEEYLIKRLSHQVGEASRLEKIARIRSWYPASVDHEDDRQVAT
WIEENYKTLDDKLKGLKLESFAQDLAKKIRSDHDNAIDGLSEVIK
3D structure
PDB1uyr Molecular Basis for the Inhibition of the Carboxyltransferase Domain of Acetyl-Coenzyme-A Carboxylase by Haloxyfop and Diclofop
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.3.4.14: biotin carboxylase.
6.4.1.2: acetyl-CoA carboxylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 D1L B W1924 F1956 L1968 G1971 G1997 G1998 V2001 V2002 W441 F473 L479 G482 G508 G509 V512 V513
BS02 D1L B G1626 A1627 G1734 I1735 Y1738 L1756 G143 A144 G251 I252 Y255 L273
Gene Ontology
Molecular Function
GO:0003989 acetyl-CoA carboxylase activity
GO:0016874 ligase activity

View graph for
Molecular Function
External links
PDB RCSB:1uyr, PDBe:1uyr, PDBj:1uyr
PDBsum1uyr
PubMed15079078
UniProtQ00955|ACAC_YEAST Acetyl-CoA carboxylase (Gene Name=ACC1)

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