Structure of PDB 1uvq Chain B

Receptor sequence
>1uvqB (length=181) Species: 9606 (Homo sapiens) [Search protein sequence]
SPEDFVFQFKGMCYFTNGTERVRLVTRYIYNREEYARFDSDVGVYRAVTP
QGRPDAEYWNSQKEVLEGTRAELDTVCRHNYEVAFRGILQRRVEPTVTIS
PSNLLVCSVTDFYPGQIKVRWFRNDQEETAGVVSTPLIRNGDWTFQILVM
LEMTPQRGDVYTCHVEHPSLQSPITVEWRAQ
3D structure
PDB1uvq Crystal Structure of Hla-Dq0602 that Protects Against Type 1 Diabetes and Confers Strong Susceptibility to Narcolepsy
ChainB
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B F11 Y30 D57 Y60 W61 E74 T77 V78 N82 V85 F9 Y28 D55 Y58 W59 E72 T75 V76 N80 V83
BS02 FUC B T21 E22 T19 E20
BS03 ZN B D76 H81 D74 H79
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:1uvq, PDBe:1uvq, PDBj:1uvq
PDBsum1uvq
PubMed14769912
UniProtP01920|DQB1_HUMAN HLA class II histocompatibility antigen, DQ beta 1 chain (Gene Name=HLA-DQB1)

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