Structure of PDB 1uu2 Chain B

Receptor sequence
>1uu2B (length=318) Species: 2336 (Thermotoga maritima) [Search protein sequence]
EKRDKTYLALNENPFPFPEDLVDEVFRRLNSDALRIYYDSPDEELIEKIL
SYLDTDFLSKNNVSVGNGADEIIYVMMLMFDRSVFFPPTYSCYRIFAKAV
GAKFLEVPLTKDLRIPEVNVGEGDVVFIPNPNNPTGHVFEREEIERILKT
GAFVALDEAYYEFHGESYVDFLKKYENLAVIRTFSKAFSLAAQRVGYVVA
SEKFIDAYNRVRLPFNVSYVSQMFAKVALDHREIFEERTKFIVEERERMK
SALREMGYRITDSRGNFVFVFMEKEEKERLLEHLRTKNVAVRSFREGVRI
TIGKREENDMILRELEVF
3D structure
PDB1uu2 Structural Studies of the Catalytic Reaction Pathway of a Hyperthermophilic Histidinol-Phosphate Aminotransferase
ChainB
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.6.1.9: histidinol-phosphate transaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PMP B Y53 F334 Y37 F318
BS02 PMP B G84 A85 D86 Y106 D173 Y176 T199 S201 K202 R210 G68 A69 D70 Y90 D157 Y160 T183 S185 K186 R194
Gene Ontology
Molecular Function
GO:0004400 histidinol-phosphate transaminase activity
GO:0008483 transaminase activity
GO:0016740 transferase activity
GO:0030170 pyridoxal phosphate binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0000105 L-histidine biosynthetic process
GO:0009058 biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:1uu2, PDBe:1uu2, PDBj:1uu2
PDBsum1uu2
PubMed15007066
UniProtQ9X0D0|HIS8_THEMA Histidinol-phosphate aminotransferase (Gene Name=hisC)

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