Structure of PDB 1un0 Chain B

Receptor sequence
>1un0B (length=439) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
ELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLVE
FMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSV
EVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTATW
TLSNLCRGKKPQPDWSVVSQALPTLAKLIYSMDTETLVDACWAISYLSDG
PQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQVV
INAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIPP
LVKLLEVAEDKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLL
EIADNRIIEVTLDALENILKMGEADKEARGLNINENADFIEKAGGMEKIF
NCQQNENDKIYEKAYKIIETYFGEEEDAVDETMAPQNAG
3D structure
PDB1un0 Structural Basis for Nup2P Function in Cargo Release and Karyopherin Recycling in Nuclear Import
ChainB
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B W237 S240 R244 G245 D276 W279 Y283 D286 G287 T317 P318 R321 V327 T328 G329 T334 E360 W363 N367 I368 A370 E402 W405 W150 S153 R157 G158 D189 W192 Y196 D199 G200 T230 P231 R234 V240 T241 G242 T247 E273 W276 N280 I281 A283 E315 W318
Gene Ontology
Molecular Function
GO:0061608 nuclear import signal receptor activity
Biological Process
GO:0006606 protein import into nucleus
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1un0, PDBe:1un0, PDBj:1un0
PDBsum1un0
PubMed14532109
UniProtQ02821|IMA1_YEAST Importin subunit alpha (Gene Name=SRP1)

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