Structure of PDB 1ukw Chain B

Receptor sequence
>1ukwB (length=379) Species: 274 (Thermus thermophilus) [Search protein sequence]
IDFSLTEEQRQLQALARRFAKEVILPVAQEYDEKEEVPWPVIEKLHEVGL
LNAIIPEEYGGMGLKMLDEVIVGEELAYACMGIYTIPMASDLGITPVLLA
GTEEQKERFLRPLTEKPALAAFALSEPGNGSDAAALKTRAIRQGDHYVLN
GTKMWISNGGEAEWVVVFATVNPELRHKGVVALVVERGTPGFKAIKIHGK
MGQRASGTYELVFEDVKVPVENRLGEEGEGFKIAMQTLNKTRIPVAAGSV
GVARRALDEARKYAKEREAFGEPIANFQAIQFKLVDMLIGIETARMYTYY
AAWLADQGLPHAHASAIAKAYASEIAFEAANQAIQIHGGYGYVREFPVEK
LLRDVKLNQIYEGTNEIQRLIIARHILAA
3D structure
PDB1ukw Crystal structure of Thermus thermophilus medium-chain acyl-CoA dehydrogenase
ChainB
Resolution2.4 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) L155 S156 T272 E393 R405
Catalytic site (residue number reindexed from 1) L124 S125 T241 E362 R374
Enzyme Commision number 1.3.99.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CO B D176 H177 D145 H146
BS02 FAD B F153 L155 S156 G161 S162 W186 S188 K231 L388 Y392 E393 T395 E397 L401 F122 L124 S125 G130 S131 W155 S157 K200 L357 Y361 E362 T364 E366 L370
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003995 acyl-CoA dehydrogenase activity
GO:0016491 oxidoreductase activity
GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
GO:0050660 flavin adenine dinucleotide binding

View graph for
Molecular Function
External links
PDB RCSB:1ukw, PDBe:1ukw, PDBj:1ukw
PDBsum1ukw
PubMed
UniProtQ72JJ3

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