Structure of PDB 1uad Chain B

Receptor sequence
>1uadB (length=173) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGE
EVQIDILDTAGQEDYAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQ
ILRVKEDENVPFLLVGNKSDLEDKRQVSVEEAKNRAEQWNVNYVETSAKT
RANVDKVFFDLMREIRARKMEDS
3D structure
PDB1uad Structural basis of the interaction between RalA and Sec5, a subunit of the Sec6/8 complex
ChainB
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG B S28 T46 S18 T36
BS02 GNP B G24 V25 G26 K27 S28 A29 F39 Y43 T46 G71 N127 K128 D130 L131 S157 A158 G14 V15 G16 K17 S18 A19 F29 Y33 T36 G61 N117 K118 D120 L121 S147 A148 MOAD: Ka=7260000M^-1
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0007165 signal transduction
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:1uad, PDBe:1uad, PDBj:1uad
PDBsum1uad
PubMed12839989
UniProtP11233|RALA_HUMAN Ras-related protein Ral-A (Gene Name=RALA)

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